Package: grandR 0.2.5

Florian Erhard

grandR: Comprehensive Analysis of Nucleotide Conversion Sequencing Data

Nucleotide conversion sequencing experiments have been developed to add a temporal dimension to RNA-seq and single-cell RNA-seq. Such experiments require specialized tools for primary processing such as GRAND-SLAM, (see 'Jürges et al' <doi:10.1093/bioinformatics/bty256>) and specialized tools for downstream analyses. 'grandR' provides a comprehensive toolbox for quality control, kinetic modeling, differential gene expression analysis and visualization of such data.

Authors:Florian Erhard [aut, cre], Teresa Rummel [ctb], Lygeri Sakellaridi [ctb], Kevin Berg [ctb]

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grandR/json (API)
NEWS

# Install 'grandR' in R:
install.packages('grandR', repos = c('https://erhard-lab.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/erhard-lab/grandr/issues

On CRAN:

5.16 score 8 stars 18 scripts 239 downloads 163 exports 40 dependencies

Last updated 10 months agofrom:5527612e00. Checks:ERROR: 1 WARNING: 8. Indexed: yes.

TargetResultDate
Doc / VignettesFAILNov 05 2024
R-4.5-win-x86_64WARNINGNov 05 2024
R-4.5-linux-x86_64WARNINGNov 05 2024
R-4.4-win-x86_64WARNINGNov 05 2024
R-4.4-mac-x86_64WARNINGNov 05 2024
R-4.4-mac-aarch64WARNINGNov 05 2024
R-4.3-win-x86_64WARNINGNov 05 2024
R-4.3-mac-x86_64WARNINGNov 05 2024
R-4.3-mac-aarch64WARNINGNov 05 2024

Exports:AddAnalysisAddGenePlotAddGlobalPlotAddSlotAnalysesAnalyzeGeneSetsApplyContrastsas.Seurat.grandRCalibrateEffectiveLabelingTimeKineticFitCalibrateEffectiveLabelingTimeMatchHalflivesClassifyGenesColdataColdata<-ColumnsComputeAbsoluteComputeColumnStatisticsComputeExpressionPercentageComputeNonConstantParamComputeNtrCIComputeNtrPosteriorLowerComputeNtrPosteriorQuantileComputeNtrPosteriorUpperComputePseudoNtrComputeSteadyStateHalfLivesComputeSummaryStatisticsConditionCondition<-Correct4sUDropoutHLFactorCorrect4sUDropoutHLSplineCreatePdfsCreatePdfsComparisonCreatePdfsParametersCreatePdfsProfilesDefaultSlotDefaultSlot<-Deferdensity2dDESeq2BICDesignDesignSemanticsDropAnalysisDropPlotsDropSlotestimate.dispersionEstimate4sUDropoutPercentageEstimate4sUDropoutPercentageForSampleEstimateRegulationEvaluateNonConstantParamf.newf.nonconstf.nonconst.linearf.old.equif.old.nonequiFilterGenesFindno4sUPairsFindReferencesFitKineticsFitKineticsGeneLeastSquaresFitKineticsGeneLogSpaceLinearFitKineticsGeneNtrFitKineticsGeneSnapshotFitKineticsPulseRFitKineticsSnapshotFormatCorrelationGeneInfoGeneInfo<-GenesGetAnalysisTableGetContrastsGetDataGetDiagnosticParametersGetMatrixGetPairContrastsGetSignificantGenesGetSummarizeMatrixGetTablegrandRis.grandRIsParallelIsSparsekinetics2vectorLFCLikelihoodRatioTestListGeneSetsMakeColdataMAPlotmerge.grandRMetadataNormalizeNormalizeBaselineNormalizeFPKMNormalizeRPMNormalizeTPMPairwisePairwiseDESeq2plapplyPlot4sUDropoutPlot4sUDropoutAllPlot4sUDropoutDeferAllPlot4sUDropoutRankPlot4sUDropoutRankAllPlot4sUDropoutRankDeferAllPlotAnalysesPlotConversionFreqPlotGenePlotGeneGroupsBarsPlotGeneGroupsPointsPlotGeneOldVsNewPlotGeneProgressiveTimecoursePlotGeneSnapshotTimecoursePlotGeneTotalVsNtrPlotGlobalPlotHeatmapPlotMismatchPositionForSamplePlotMismatchPositionForTypePlotModelCompareConvPlotModelCompareErrPlotModelCompareErrPriorPlotModelCompareLLPlotModelCompareNtrPlotModelConvPlotModelErrPlotModelLabelTimeCoursePlotModelNtrPlotModelShapePlotPCAPlotProfileLikelihoodPlotsPlotScatterPlotSimulationPlotTypeDistributionPoolColumnspsapplyReadCountsReadFeatureCountsReadGRANDReadGRAND3ReadNewTotalRenameColumnsRotatateAxisLabelsSaveNtrSlotScaleSemantics.concentrationSemantics.timeServeGrandRSetParallelSimulateKineticsSimulateReadsForSampleSimulateTimeCourseSimulateTimeCourseNonConstantSlotsstructure2vectorSwapColumnsTitleToIndexTransform.logFCTransform.noTransform.VSTTransform.ZTransformSnapshotUpdateSymbolsUseNtrSlotVulcanoPlot

Dependencies:bitopsclicolorspacecowplotfansifarverggplot2gluegtableisobandlabelinglatticelfclifecyclemagrittrMASSMatrixmgcvminpack.lmmunsellnlmenumDerivpatchworkpillarpkgconfigplyrR6RColorBrewerRcppRCurlreshape2rlangscalesstringistringrtibbleutf8vctrsviridisLitewithr

Getting started

Rendered fromgetting-started.Rmdusingknitr::rmarkdownon Nov 05 2024.

Last update: 2023-02-27
Started: 2022-09-15