Package: grandR
Version: 0.2.7
Title: Comprehensive Analysis of Nucleotide Conversion Sequencing Data
Authors@R: c(
    person("Florian", "Erhard", email = "Florian.Erhard@informatik.uni-regensburg.de", role = c("aut", "cre"), comment = c(ORCID = "0000-0002-3574-6983")),
    person("Teresa", "Rummel", email = "Teresa.Rummel@uni-wuerzburg.de", role = "ctb"),
    person("Julian", "Selke", email = "Julian-Andreas.Selke@informatik.uni-regensburg.de", role = "ctb")
    )
Description: Nucleotide conversion sequencing experiments have been
        developed to add a temporal dimension to RNA-seq and
        single-cell RNA-seq. Such experiments require specialized tools
        for primary processing such as GRAND-SLAM, (see 'Jürges et al'
        <doi:10.1093/bioinformatics/bty256>) and specialized tools for
        downstream analyses. 'grandR' provides a comprehensive toolbox
        for quality control, kinetic modeling, differential gene
        expression analysis and visualization of such data. Fast
        Wilcoxon tests are supported via the 'presto' package
        (available at https://github.com/immunogenomics/presto).
Author: Florian Erhard [aut, cre]
        (<https://orcid.org/0000-0002-3574-6983>), Teresa Rummel [ctb],
        Julian Selke [ctb]
Maintainer: Florian Erhard
 <Florian.Erhard@informatik.uni-regensburg.de>
License: Apache License (>= 2)
Encoding: UTF-8
URL: https://github.com/erhard-lab/grandR
BugReports: https://github.com/erhard-lab/grandR/issues
Additional_repositories: https://immunogenomics.github.io/presto/
Depends: R (>= 3.5.0)
Imports: stats, Matrix, rlang, ggplot2, grDevices, patchwork, RCurl,
        plyr, parallel, reshape2, MASS, scales, cowplot, minpack.lm,
        lfc, labeling, methods, utils, numDeriv
Suggests: knitr, rmarkdown, circlize, Seurat, ComplexHeatmap, ggrepel,
        DESeq2, S4Vectors, data.table, clusterProfiler, biomaRt,
        msigdbr, fgsea, rclipboard, cubature, DT, shinyjs, shinyjqui,
        RColorBrewer, gsl, htmltools, matrixStats, VGAM, quantreg,
        graphics, shiny, ggrastr, viridisLite, deSolve, presto
RoxygenNote: 7.3.3
VignetteBuilder: knitr
Config/pak/sysreqs: make libicu-dev
Repository: https://erhard-lab.r-universe.dev
Date/Publication: 2026-01-13 21:59:25 UTC
RemoteUrl: https://github.com/erhard-lab/grandr
RemoteRef: HEAD
RemoteSha: b8d45e98a59a0ab5907376e0bc27aa2b092fc851
NeedsCompilation: yes
Packaged: 2026-09-27 20:48:14 UTC; root